Chemical Industry Journal - article

Micropore Technologies has identified several recurring challenges in the scale-up process. By understanding these common mistakes, manufacturers can implement more reliable strategies to ensure consistent particle engineering from development through to manufacturing.

In the pharmaceutical and specialty chemical industries, complex emulsions – such as water-in-oil-in-water (W/O/W) double emulsions, microspheres, and encapsulated fragrances – are notoriously difficult to move from the laboratory to commercial production.

While a formulation may perform perfectly at a 50mL scale, increasing that volume often necessitates manufacturing trade-offs that compromise product integrity, triggering lengthy re-optimisation processes to resolve.

Read the full article here…

https://www.chemicalindustryjournal.co.uk/common-mistakes-and-solutions-for-scaling-up-complex-emulsions